pip install mido
 Downloading mido-1.3.2-py3-none-any.whl (54 kB)
 Downloading packaging-23.2-py3-none-any.whl (53 kB)
Installing collected packages: packaging, mido
Successfully installed mido-1.3.2 packaging-23.2

mido 官网文档

pip intall pygame
 pygame  2.5.2

安装文档 D:/Python39/Lib/site-packages/pygame/docs/generated/index.html

编写  test1_mido.py  如下

# -*- coding: utf-8 -*- from mido import Message, MidiFile, MidiTrack   mid = MidiFile()    # 创建MIDI文件 track = MidiTrack() # 创建一个音轨 mid.tracks.append(track)  track.append(Message("program_change", channel=0, program=2, time=0)) # 创建各个音符，并添加到音轨中 map1 = {'C4':60, 'D4':62, 'E4':64, 'F4':65, 'G4':67, 'A4':69, 'B4':71, 'C5':72} # do: C4 = 60 track.append(Message("note_on", note=60, velocity=96, time=0)) track.append(Message("note_off", note=60, velocity=0, time=500)) # re: D4 = 62  track.append(Message("note_on", note=62, velocity=96, time=0)) track.append(Message("note_off", note=62, velocity=0, time=500)) # mi: E4 = 64 track.append(Message("note_on", note=64, velocity=96, time=0)) track.append(Message("note_off", note=64, velocity=0, time=500)) # fa: F4 = 65 track.append(Message("note_on", note=65, velocity=96, time=0)) track.append(Message("note_off", note=65, velocity=0, time=500)) # sol:G4 = 67 track.append(Message("note_on", note=67, velocity=96, time=0)) track.append(Message("note_off", note=67, velocity=0, time=500)) # la: A4 = 69 track.append(Message("note_on", note=69, velocity=96, time=0)) track.append(Message("note_off", note=69, velocity=0, time=500)) # si: B4 = 71 track.append(Message("note_on", note=71, velocity=96, time=0)) track.append(Message("note_off", note=71, velocity=0, time=500)) # do^: C5 = 72 track.append(Message("note_on", note=72, velocity=96, time=0)) track.append(Message("note_off", note=72, velocity=0, time=500))  mid.save("test1.mid") 

运行 python test1_mido.py  生成文件 test1.mid

查看 mid文件内容 （Message），编写  mido_msg.py  如下

# -*- coding: utf-8 -*- """ https://mido.readthedocs.io/en/latest/ """ import os import sys from tkinter import filedialog from mido import MidiFile  # main() if len(sys.argv) ==1:     filetypes = [('mid file','.mid')]     f1 = filedialog.askopenfilename(initialdir='D:/Music', filetypes=filetypes) elif len(sys.argv) ==2:     f1 = sys.argv[1] else:     print('usage: python mido_msg.py file1.mid')     sys.exit(1)  if not os.path.exists(f1):     print(f"{f1} is not exists.")     sys.exit(2)  fn,ext = os.path.splitext(f1) if ext.lower() != '.mid':     print('ext is not .mid ')     sys.exit(2)  # mid = MidiFile(f1) with MidiFile(f1) as mid:     for msg in mid:         print(msg) 

运行  python mido_msg.py  happy_birthday.mid 

编写  play_mid.py  如下

# -*- coding: utf-8 -*- import os import sys import time from tkinter import filedialog import traceback import pygame from pygame import mixer  def mixer_init():     freq = 44100     bitsize = -16     channels = 2     buffer = 2048     mixer.init(freq, bitsize, channels, buffer)     # optional volume 0 to 1.0     mixer.music.set_volume(0.9)  def play_mid(file):     if mixer.music.get_busy():         mixer.music.fadeout(1000)         mixer.music.stop()      clock = pygame.time.Clock()     try:         mixer.music.load(file)     except:         print(traceback.format_exc())     mixer.music.play()     while mixer.music.get_busy():         clock.tick(30)  # main() if len(sys.argv) ==1:     filetypes = [('mid file','.mid')]     f1 = filedialog.askopenfilename(initialdir='D:/Music', filetypes=filetypes) elif len(sys.argv) ==2:     f1 = sys.argv[1] else:     print('usage: python play_mid.py file1.mid')     sys.exit(1)  if not os.path.exists(f1):     print(f"{f1} is not exists.")     sys.exit(2)  fn,ext = os.path.splitext(f1) if ext.lower() not in ('.mid','.mp3'):     print('ext is not (.mid , .mp3)')     sys.exit(2)  time1 = time.time() print(f1) mixer_init() try:     play_mid(f1) except KeyboardInterrupt as ex:     # if user hits Ctrl+C then exit     # (works only in console mode)     mixer.music.fadeout(1000)     mixer.music.stop()     raise SystemExit from ex mixer.music.stop() time2 = time.time() print("run time: %.3f s" % (time2-time1)) 

运行 python play_mid.py test1.mid

详细参阅：Python编曲实践（一）：通过Mido和PyGame来编写和播放单轨MIDI文件

MidiEditor 打开 test1.mid 文件